TMPH hydrochloride salt form · hydrochloride · Parent TMPH
nAChR-IN-1 is a tetramethylpiperidine heptanoate, a selective nicotinic acetylcholine receptor inhibitor.
For research use only. Not for human or veterinary use.
Description
nAChR-IN-1 (hydrochloride) is a tetramethylpiperidine heptanoate, a selective nicotinic acetylcholine receptor (nAChR) inhibitor that inhibits nAChRs lacking α5, α6, or β3 subunits. nAChR-IN-1 has the effect of preventing nerve disorder, can be used for nicotinic acetylcholine receptor dysfunction or neurological disorders research.
Biological activity
TMPH hydrochloride is a potent non-competitive antagonist of neuronal nicotinic ACh receptors (nAChRs). Produces long-lasting inhibition of neuronal nAChRs formed by the combination of the most abundant α and β subunits (i.e. α3, α4 and β2, β4 respectively). Displays little inhibition of muscle-type (α1β1γδ) or α7 receptors.
Identifiers
- SMILES
-
CCCCCCC(OC1CC(C)(NC(C)(C)C1)C)=O.[H]Cl - InChIKey
-
XIDDVJIJIFWGIX-UHFFFAOYSA-N
Specifications
- MW (average)
- 305.8840
- Formula
- C16H32ClNO2
- CAS No.
- 849461-91-2
- Physical state
- Solid
- Color
- White to off-white
- Shipping
- Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
- Storage
- Please store the product under the recommended conditions in the Certificate of Analysis.
Solubility
Soluble in DMSO