BiochemProbe — Life Science Research Reagents

AZD2389 free base · Synonyms: AZD-2389 · AZD 2389

AZD2389 is a potent and orally active FAP inhibitor.

For research use only. Not for human or veterinary use.

Target FAP
Research area Metabolic Disease
Purity >98% Stock Inquire
Data Sheet SDS COA

AZD2389 structure

CAS No.: 2791472-12-1

Download structure (.mol)

Pack sizes & pricing

Size Price SKU Stock
50 mg USD 458.00 BP-02054-50mg In stock Get quote
100 mg USD 650.00 BP-02054-100mg In stock Get quote
250 mg USD 958.00 BP-02054-250mg In stock Get quote
500 mg USD 1,358.00 BP-02054-500mg In stock Get quote
1 g USD 1,880.00 BP-02054-1g In stock Get quote
Custom Size Bulk Inquiry

Description

AZD2389 is a potent and orally active FAP inhibitor. AZD2389 can be used for the study of metabolic dysfunction-associated steatohepatitis .

Biological activity

In Vivo AZD2389 (29 week) increases intact α2-antiplasmin and improvements in non-alcoholic fatty liver disease (NAFLD) activity score and histological fibrosis in cynomolgus monkeys with diet induced, biopsy confirmed metabolic dysfunction-associated steatohepatitis (MASH) (F1/2 fibrosis).

Identifiers

SMILES
O=C(N1[C@@H](CSC1)C#N)CNC(C2=CC=NC3=C2C=C(N4CCOCC4)C=C3)=O
InChIKey
GECJKRWOVGXGCO-OAHLLOKOSA-N

Specifications

MW (average)
411.4770
Formula
C20H21N5O3S
CAS No.
2791472-12-1
Physical state
Solid
Color
Light yellow to yellow
Shipping
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage
Powder 4℃ 2 years; In solvent -20℃ 1 month;

Solubility

Soluble in DMSO， >50 mg/mL

Documents

References

[1]. AZD2389, a first in class candidate drug for the treatment of metabolic dysfunction-associated steatohepatitis.

Same research area

Search Metabolic Disease