Paltusotine free base · Synonyms: CRN00808
Paltusotine is an orally active, nonpeptide selective somatostatin type 2 receptor agonist.
For research use only. Not for human or veterinary use.
Paltusotine structure
CAS No.: 2172870-89-0
Pack sizes & pricing
| Size | Price | SKU | Stock | |
|---|---|---|---|---|
| 100 mg | USD 380.00 | BP-01984-100mg | In stock | Get quote |
| 250 mg | USD 645.00 | BP-01984-250mg | In stock | Get quote |
| 500 mg | USD 968.00 | BP-01984-500mg | In stock | Get quote |
| 1 g | USD 1,450.00 | BP-01984-1g | In stock | Get quote |
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Description
Paltusotine (CRN00808) is an orally active, nonpeptide selective somatostatin type 2 (SST2) receptor agonist. Paltusotine has the potential for maintaining GH and IGF-1 levels after depot somatostatin receptor ligand therapy.
Biological activity
ALZ-801 (oral administration; 172?mg/kg; single dose) exhibits mean AUCt values of 58,758 and? 5841 ng/ml.h in plasma and brain, respectively. The ALZ-801: Tramiprosate ratio in plasma and brain is 1.8 and 3.1, respectively in male CD-1 mice
Identifiers
- SMILES
-
N#CC1=C(O)C(C2=CC3=C(N4CCC(CC4)N)C(C5=CC(F)=CC(F)=C5)=CN=C3C=C2)=CC=C1 - InChIKey
-
GHILNKWBALQPDP-UHFFFAOYSA-N
Specifications
- MW (average)
- 456.4866
- Formula
- C27H22F2N4O
- CAS No.
- 2172870-89-0
- Physical state
- Solid
- Color
- white to yellow
- Shipping
- Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
- Storage
- 4°C, sealed storage, away from moisture
Solubility
Soluble in H2O : 30 mg/mL