MAGL-IN-4 free base
MAGL-IN-4 is one of the monoacylglycerol lipase (MAGL) inhibitors in central nervous system-related diseases.
For research use only. Not for human or veterinary use.
MAGL-IN-4 structure
CAS No.: 2135785-20-3
Pack sizes & pricing
| Size | Price | SKU | Stock | |
|---|---|---|---|---|
| 25 mg | USD 408.00 | BP-01974-25mg | In stock | Get quote |
| 50 mg | USD 538.00 | BP-01974-50mg | In stock | Get quote |
| 100 mg | USD 726.00 | BP-01974-100mg | In stock | Get quote |
| 250 mg | USD 1,080.00 | BP-01974-250mg | In stock | Get quote |
| 500 mg | USD 1,458.00 | BP-01974-500mg | In stock | Get quote |
| 1 g | USD 1,968.00 | BP-01974-1g | In stock | Get quote |
Need another size or custom synthesis? Request a quote.
Description
MAGL-IN-4 is one of the monoacylglycerol lipase (MAGL) inhibitors in central nervous system-related diseases.
Biological activity
In vitro: MAGL-IN-4 showed potent in vitro MAGL inhibitory activity (IC50 6.2 nM), good oral absorption and blood-brain barrier penetration. In vivo: MAGL-IN-4 showed significant pharmacodynamic changes (2-arachidonoylglycerol increase and arachidonic acid decrease) at 0.3-10 mg/kg, po. in mice.
Identifiers
- SMILES
-
O=C(N1CC(C1)OCC2=CC(Cl)=C(C=C2)C)[C@@H]3C[C@@]4(COC(N4)=O)C3 - InChIKey
-
AKBHYCHPWZPGAH-QGGXVJLZSA-N
Specifications
- MW (average)
- 364.8230
- Formula
- C18H21ClN2O4
- CAS No.
- 2135785-20-3
- Physical state
- Solid
- Color
- White to off-white
- Shipping
- Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
- Storage
- Powder -20℃ 3 years; In solvent -20℃ 1 month;
Solubility
Soluble in DMSO 100 mg/mL