(4'S,5'R)-6''-chloro-4'-(2-chloro-3-fluoropyridin-4-yl)-4,4-dimethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxylic acid free base · Synonyms: 1398572-08-1

These compound inhibits interaction between Mdm2 protein and p53 protein, and show anti-tumor activity.

For research use only. Not for human or veterinary use.

Purity >98% Stock Inquire

Data Sheet SDS COA

(4'S,5'R)-6''-chloro-4'-(2-chloro-3-fluoropyridin-4-yl)-4,4-dimethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxylic acid structure

CAS No.: 1398572-08-1

Download structure (.mol)

Pack sizes & pricing

Size	Price	SKU	Stock
250 mg	USD 2,950.00	BP-00851-250mg	In stock	Get quote
500 mg	USD 3,980.00	BP-00851-500mg	Inquire	Get quote
1 g	Inquire	BP-00851-1g	In stock	Inquire

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Description

These compound inhibits interaction between Mdm2 protein and p53 protein, and show anti-tumor activity.

Identifiers

SMILES: O=C1C2(C3(N[C@@H](C(O)=O)[C@@H]2C=4C(F)=C(Cl)N=CC4)CCC(C)(C)CC3)C=5C(N1)=CC(Cl)=CC5
InChIKey: JMRACJQDFUOCEO-LPOVVEPHSA-N

Specifications

MW (average): 492.3700
Formula: C₂₄H₂₄Cl₂FN₃O₃
CAS No.: 1398572-08-1
Physical state: Solid
Color: White to off-white
Shipping: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage: Powder 4℃ 2 years; In solvent -20℃ 1 month;

Solubility

Soluble in DMSO

Documents

References

[1]. WO2012121361 A1